OFFICIAL PAGE: AudioRose
AudioRose, from Zerebrix, is a standalone application for separating your audio. According to their website, "Split any song up without restrictions into 5 stems: Guitar, Vocals, Drums, Bass, and accompaniment. AudioRose is one of the first stem extractors to isolate the guitar instrument.." AudioRose is available for both macOS and Windows. A free trial is available. A couple of subscription pricing plans are available as is a perpetual license. Full details at the link above.
Screenshot courtesy of Zerebrix